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dBET57
CAS No. : 1883863-52-2
Biological Activity:dBET57 is a potent and selective degrader of BRD4BD1 based on the PROTAC technology. dBET57 mediates recruitment to the CRL4Cereblon E3 ubiquitin ligase, with a DC50/5h of 500 nM for BRD4BD1, and is inactive on BRD4BD2.
Research Area:Cancer
Targets:Epigenetic Reader Domain|PROTACs
Related Screening Libraries:Bioactive Compound Library Plus;
Related Small Molecules:PROTAC Sirt2 Degrader-1;DB0614;RVX-297;BRD4 Inhibitor-19;UNC6349 (Ket2);PROTAC VEGFR-2 degrader-2;Curcumin;GSK6853;dTAGV-1-NEG;CCT367766 formic;GSK4028;SR-0813;HDAC6 degrader-1;PROTAC Axl Degrader 2;Inobrodib;PhosTAC7;MS98;Apabetalone;OF-1;I-CBP112;JPS014;PROTAC PARP1 degrader;A-485;MD-224;PLX51107;FKBP12 PROTAC dTAG-7;I-BET151;SJ10542;MS8815;GSK040
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