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Chroman 1
CAS No. : 1273579-40-0
Biological Activity：Chroman 1 is a highly potent and selective ROCK inhibitor. Chroman 1 is more potent against ROCK2 (IC50=1 pM) than ROCK1 (IC50=52 pM). Chroman 1 also has inhibitory activity against MRCK, with an IC50 of 150 nM[2].
Research Area：Cardiovascular Disease
Targets：ROCK
Related Screening Libraries:Bioactive Compound Library Plus;Cell Cycle/DNA Damage Compound Library;Kinase Inhibitor Library;Stem Cell Signaling Compound Library;TGF-beta/Smad Compound Library;Anti-Aging Compound Library;Reprogramming Compound Library;Anti-Cardiovascular Disease Compound Library;Cytoskeleton Compound Library;Targeted Diversity Library;Anti-Pulmonary Fibrosis Compound Library;Cancer Stem Cells Compound Library;
Related Small Molecules:Ripasudil free base;PF-4950834;ROCK-IN-4;GSK-25;AT13148;LX7101;Y-27632 dihydrochloride;RKI-1447;AS1892802;SB-772077B dihydrochloride;BDP5290;Fasudil;3-(4-Pyridyl)indole;GSK429286A;Verosudil;CRT0066854;H-1152 dihydrochloride;ROCK2-IN-5;Cotosudil;ZINC00881524;Hydroxyfasudil hydrochloride;HA-100 hydrochloride;Thiazovivin;Rho-Kinase-IN-1;Y-33075;BAY-549
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