BETd-260

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BETd-260

CAS No. : 2093388-62-4

Biological Activity:BETd-260 (ZBC 260) is a PROTAC connected by ligands for Cereblon and BET, with as low as 30 pM against BRD4 protein in RS4;11 leukemia cell line. BETd-260 potently suppresses cell viability and robustly induces apoptosis in hepatocellular carcinoma (HCC) cells[2].

Research Area:Cancer

Targets:Epigenetic Reader Domain|PROTACs|Apoptosis

Related Screening Libraries:Bioactive Compound Library Plus;

Related Small Molecules:Physalin A;Bomedemstat ditosylate;PROTAC Sirt2 Degrader-1;DB0614;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;RVX-297;Lobetyolin;BRD4 Inhibitor-19;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;UNC6349 (Ket2);Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5

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