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ASR-490
CAS No. : 2690312-67-3
Biological Activity：ASR-490 reduces the viability of HCT116 and SW620 cells by downregulating Notch1 signaling. ASR-490 overcomes Notch1 overexpression and inhibits the growth of HCT/Notch1 transfectants. ASR-490 inhibits the tumor growth in control (pCMV/HCT116) and Notch1/HCT116 in xenotransplanted mice.
Research Area：Cancer
Targets：Notch
Related Small Molecules:ZLDI-8;Crenigacestat;FLI-06;JI051;Demcizumab;Notch inhibitor 1;Tarextumab;Notch 1 TFA;Bruceine D;Psoralidin;YO-01027 (GMP);Brontictuzumab;Semagacestat;BMS-983970;SAHM1 TFA;LY-411575;CB-103;Yhhu-3792;Jagged-1 (188-204) (TFA);Tangeretin;Z-Ile-Leu-aldehyde;tCFA15
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