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Articaine hydrochloride
CAS No. : 23964-57-0
Biological Activity：Articaine hydrochloride (Hoe-045) is an amide anaesthetic containing an ester group, reversibly binding to the α-subunit of the voltage-gated sodium channels within the inner cavity of the nerve, can provide effective pain relief. Articaine hydrochloride ameliorates LPS-induced acute kidney injury via inhibition of NF-ĸB activation and the NLRP3 inflammasome pathway[2][3].
Research Area：Neurological Disease
Targets：NF-κB|Sodium Channel|NOD-like Receptor (NLR)
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