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8-CPT-2Me-cAMP sodium

CAS No. : 634207-53-7

Biological Activity：8-CPT-2Me-cAMP sodium is a selective activator of exchange proteins activated by cAMP (Epac), the cAMP sensitive guanine nucleotide exchange factors (GEFs) for the small GTPases Rap1 and Rap2. 8-CPT-2Me-cAMP sodium activates Epac1 (EC₅₀ = 2.2 μM), but not PKA (EC₅₀> 10 μM). 8-CPT-2Me-cAMP sodium stimulates Epac-mediated Ca²⁺ release in pancreatic β-cells in vitro^[2].

Research Area：Others

Targets：Ras

Related Small Molecules:Deltarasin hydrochloride;ZINC09659342;KRAS G12C inhibitor 56;CCG-232601;KRAS G12D inhibitor 14;1A-116;KRAS G12D inhibitor 10;KRAS G12C inhibitor 20;KRAS G12C inhibitor 24;RM-018;KRAS G12C inhibitor 14;APS6-45;6H05;KRpep-2d TFA;KRAS G12C inhibitor 33;KRAS G12C inhibitor 53;K-Ras-IN-1;KRAS G12C inhibitor 41;KRAS G12C inhibitor 26;KRAS G12C inhibitor 16;KRAS inhibitor-11;SOS1-IN-13;BQU57;ZCL278;Digeranyl bisphosphonate;KRAS inhibitor-7;SOS1 activator 1;KRAS inhibitor-14;SAH-SOS1A

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