December 22, 2022 - epigenetics modulation frontier

Guanfu base I

Posted on December 22, 2022 by haoyuan2014

For research use only. We do not sell to patients. Guanfu base I CAS No. : 110225-59-7 Biological Activity：Guanfu base I (Acorine) is an active metabolite of Guanfu base A, isolated from Aconitum coreanum, and has a potent anti-arrhythmic effect. Research Area：Cardiovascular Disease Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose […]

RI-962

Posted on December 22, 2022 by haoyuan2014

For research use only. We do not sell to patients. RI-962 CAS No. : 2763831-53-2 Biological Activity：RI-962 is a potent and selective receptor-interacting protein kinase 1 (RIPK1) inhibitor. RI-962 inhibits RIPK1 with an IC50 value of 35.0 nM. RI-962 can be used for the research of nervous system diseases and inflammatory diseases. Research Area：Inflammation/Immunology|Neurological Disease Targets：Necroptosis|RIP […]

LeuRS-IN-1 hydrochloride

Posted on December 22, 2022 by haoyuan2014

For research use only. We do not sell to patients. LeuRS-IN-1 hydrochloride CAS No. : 1364683-67-9 Biological Activity：LeuRS-IN-1 hydrochloride is a potent, orally active M. tuberculosis leucyl-tRNA synthetase (M.tb LeuRS) inhibitor. LeuRS-IN-1 hydrochloride has IC50 and Kd values of 0.06 μM, 0.075 μM for M.tb LeuRS, respectively. LeuRS-IN-1 hydrochloride inhibits human cytoplasmic LeuRS (IC50=38.8 μM), […]

16-Ketodehydroepiandrosterone-d5

Posted on December 22, 2022 by haoyuan2014

For research use only. We do not sell to patients. 16-Ketodehydroepiandrosterone-d5 Biological Activity：16-Ketodehydroepiandrosterone-d5 is the deuterium labeled 16-Ketodehydroepiandrosterone. Research Area：Others Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid mercapturate-d3;FLAG peptide;Neocurdione Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC | Isotope-Labeled Compounds | […]

N-Valproylglycine

Posted on December 22, 2022 by haoyuan2014

For research use only. We do not sell to patients. N-Valproylglycine CAS No. : 88321-07-7 Biological Activity：N-Valproylglycine is a Glycine (HY-Y0966) derivative. Research Area：Others Targets：Others Related Small Molecules:Immune initiator-1;Obiltoxaximab;DIBAC-GGFG-NH2CH2-Dxd;Cyanine5.5 maleimide chloride;Cymarin;Z-Glycine;2-Deoxy-2-fluoro-D-glucose-13C,d7;Water-18O;Fmoc-N-Me-D-Ala-OH;3,5-Diiodo-L-tyrosine;N3-Pen-Dde;Zimeldine-d6;Ornidazole diol;Nylidrin hydrochloride;PFI-653;N-Arachidonoyl Taurine-d4;OVA Peptide (323-339);((3-Fluorophenyl)sulfonyl)glycine;7ß-Hydroxycholesterol-d7;MALAT1-IN-1;Sibiricose A1;Mefruside-d3;Ethacrynic acid mercapturate-d3;FLAG peptide;Neocurdione Trending products：Recombinant Proteins | Bioactive Screening Libraries | Natural Products | Fluorescent Dye | PROTAC […]

K41498

Posted on December 22, 2022 by haoyuan2014

For research use only. We do not sell to patients. K41498 CAS No. : 434938-41-7 Biological Activity：K41498 is a potent and highly selective CRF2 receptor antagonist with Ki values of 0.66 nM, 0.62 nM and 425 nM for human CRF2α, CRF2β and CRF1 receptors respectively. K41498 is an analogues of antisauvagine-30 (aSvg-30), inhibits sauvagine-stimulated cAMP accumulation in hCRF2α– […]

BI-2081

Posted on December 22, 2022 by haoyuan2014

For research use only. We do not sell to patients. BI-2081 CAS No. : 1458656-71-7 Biological Activity：BI-2081 is a GPR40 (FFAR1) partial agonist (EC50: 4 nM). BI-2081 induces glucose depending insulin secretion and reduces the plasma glucose concentration. BI-2081 can be used in the research of metabolic diseases, in particular diabetes type 2. Research Area：Metabolic […]

Methyl aminolevulinate

Posted on December 22, 2022 by haoyuan2014

For research use only. We do not sell to patients. Methyl aminolevulinate CAS No. : 33320-16-0 Biological Activity：Methyl aminolevulinate is an agent used as a sensitizer in photodynamic therapy (PDT). Methyl aminolevulinate is a prodrug that can be metabolized to Protoporphyrin IX. Research Area：Cancer|Inflammation/Immunology Targets：Reactive Oxygen Species Related Small Molecules:D-α-Hydroxyglutaric acid disodium;Chitoheptaose heptahydrochloride;N-Acetyl-D-cysteine;Topoisomerase I/II inhibitor […]

E7090

Posted on December 22, 2022 by haoyuan2014

For research use only. We do not sell to patients. E7090 CAS No. : 1622204-21-0 Biological Activity：E7090 is an orally available, potent, and selective FGFR inhibitor with IC50s of 0.71 nM, 0.50 nM, 1.2 nM, and 120 nM for FGFR1/FGFR2/FGFR3/FGFR4, respectively. Research Area：Cancer Targets：FGFR Related Small Molecules:Ferulic acid-13C3;FGFR-IN-7;PP58;FGFR3-IN-1;ENMD-2076 Tartrate;R1530;FGFR3-IN-3;Tyrosine kinase-IN-1;Heparan Sulfate;Futibatinib;SU4984;Roblitinib;PD173074;PF 477736;FGFR4-IN-8;Lucitanib;Masitinib;Zoligratinib;FGFR4-IN-4;BLU9931;SM1-71;VSPPLTLGQLLS TFA;TG 100801;FGFR1 inhibitor-6 […]

(+)-Tetrabenazine

Posted on December 22, 2022 by haoyuan2014

“ For research use only. We do not sell to patients. (+)-Tetrabenazine CAS No. : 1026016-83-0 Biological Activity：(+)-Tetrabenazine ((+)-TBZ; (3R,11bR)-TBZ; (3R,11bR)-Tetrabenazine) is a reversible inhibitor of vesicular monoamine transporter 2 (VMAT-2), inhibits transport by VMAT2 with 10-fold greater potency than transport by VMAT1. target: VMAT-2 In vitro: (+)-Tetrabenazine inhibit the activity of the transporter but […]