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ML141
CAS No. : 71203-35-5
Biological Activity：ML141 (CID-2950007) is a potent, allosteric, selective and reversible non-competitive inhibitor of Cdc42 GTPase. ML141 inhibits Cdc42 wild type and Cdc42 Q61L mutant with EC50s of 2.1 and 2.6 μM, respectively. ML141 shows low micromolar potency and selectivity against other members of the Rho family of GTPases (Rac1, Rab2, Rab7). ML141 do not show cytotoxicity in multiple cell lines[2].
Research Area：Cancer
Targets：Apoptosis|Ras
Related Screening Libraries:Bioactive Compound Library Plus;Apoptosis Compound Library;GPCR/G Protein Compound Library;Kinase Inhibitor Library;Anti-Cancer Compound Library;Peptidomimetic Library;Ferroptosis Compound Library;Glutamine Metabolism Compound Library;Anti-Pancreatic Cancer Compound Library;Anti-Blood Cancer Compound Library;Angiogenesis-Related Compound Library;Anti-Liver Cancer Compound Library ;Anti-Colorectal Cancer Compound Library ;
Related Small Molecules:Physalin A;Bomedemstat ditosylate;Enpp/Carbonic anhydrase-IN-1;GK563;Calpeptin;Lobetyolin;BJE6-106;Dinaciclib;Ecteinascidin 770;MDM2-p53-IN-15;AT9283;Staurosporine;SNS-032;C188-9;ZLDI-8;Topoisomerase I/II inhibitor 3;Xevinapant;Mangiferin;Cambinol;Antioxidant agent-5;Apoptosis inducer 9;Bafetinib;Cyclovirobuxine D;STAT3-IN-10;Rigosertib sodium
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